核苷类抗病*物是人工合成的核苷酸类似物,其化学结构简单,便于修饰和合成,是发展最快的抗病*物,相继研发的一系列新的*低毒核苷类似物抗病*物已用于或将要用于hiv感染和HBV感染的*。核苷类似物从药物结构类型可分为嘌呤类和嘧啶类两大类,按药物作用主要分为抗逆转录酶(RT)病*物、抗肝炎病*物、抗疱疹病*物及抗其他病*物等。
泰诺福韦是一种无环核苷类抗病*物,具有抑制HBV多酶聚和hiv逆转录酶的作用,替诺福韦的活性成分替诺福韦双磷酸盐可通过直接竞争性地与天然脱氧核糖底物相结合而抑制病毒聚合酶,及通过插人DNA中终止链。是第一个被美国食品与药品管理局(FDA/批准应用于hiv-1感染*的核苷酸类似物。
更新日期产品编号品牌产品信息CAS号MDL号规格与纯度包装价格库存信息操作2023/01/06HY-13910
Tenofovir147127-20-65mg465元In-stock详细2023/01/06HY-13910
Tenofovir147127-20-610mg700元In-stock详细2023/01/06S1401
Tenofovir147127-20-65mg809.22元现货详细2023/01/06HY-13910
Tenofovir147127-20-650mg1400元In-stock详细2023/01/06HY-13910
Tenofovir147127-20-6100mg2100元In-stock详细2023/01/06S1401
Tenofovir147127-20-610mM(1mL in DMSO)901.67元现货详细2023/01/06T3006
Tenofovir147127-20-6>98.0%(HPLC)(T)1g475元5详细2023/01/06S1401
Tenofovir147127-20-650mg4659.79元现货详细2023/01/06T3006
Tenofovir147127-20-6>98.0%(HPLC)(T)5g1630元4详细2023/01/06XW1471272061
Afghanistan, Albania, Algeria, American Samoa, Angola, Anguilla, Antarctica, Antigua & Barbuda, Armenia, Aruba, Bahamas, Bangladesh, Barbados, Belgium, Belize, Benin, Bermuda, Bhutan, Bolivia, Bosnia & Herzegovina, Botswana, Bouvet Island, British Indian Ocean Territory, British Virgin Islands, Brunei, Burkina Faso, Burundi, Cameroon, Cape Verde, Cayman Islands, Central African Republic, Chad, Christmas Island, Cocos (Keeling) Islands, Comoros, Congo - Brazzaville, Congo - Kinshasa, Cook Islands, Czechia, Côte d’Ivoire, Djibouti, Dominica, Ecuador, El Salvador, Equatorial Guinea, Eritrea, Eswatini, Ethiopia, Falkland Islands, Faroe Islands, Fiji, French Guiana, French Polynesia, French Southern Territories, Gabon, Gambia, Gibraltar, Greenland, Grenada, Guadeloupe, Guam, Guernsey, Guinea, Guinea-Bissau, Guyana, Haiti, Heard & McDonald Islands, Honduras, Hong Kong SAR China, Hungary, Iceland, Indonesia, Isle of Man, Jersey, Kazakhstan, Kiribati, Kyrgyzstan, Laos, Lesotho, Liberia, Liechtenstein, Luxembourg, Macao SAR China, Madagascar, Malaysia, Maldives, Mali, Malta, Marshall Islands, Martinique, Mauritania, Mauritius, Mayotte, Micronesia, Moldova, Monaco, Mongolia, Montserrat, Morocco, Mozambique, Myanmar (Burma), Namibia, Nauru, New Caledonia, Nicaragua, Niger, Niue, Norfolk Island, North Macedonia, Northern Mariana Islands, Palau, Palestinian Territories, Panama, Papua New Guinea, Philippines, Pitcairn Islands, Portugal, Rwanda, Réunion, Saint Barthélemy, Samoa, San Marino, Senegal, Seychelles, Sierra Leone, Slovakia, Solomon Islands, Somalia, South Africa, South Georgia & South Sandwich Islands, South Korea, St. Helena, St. Kitts & Nevis, St. Lucia, St. Martin, St. Pierre & Miquelon, St. Vincent & Grenadines, Suriname, Svalbard & Jan Mayen, Syria, São Tomé & Príncipe, Taiwan, Province of China, Tajikistan, Tanzania, Thailand, Timor-Leste, Togo, Tokelau, Tonga, Trinidad & Tobago, Tunisia, Turkmenistan, Turks & Caicos Islands, Tuvalu, U.S. Outlying Islands, U.S. Virgin Islands, Uganda, Uruguay, Uzbekistan, Vanuatu, Vatican City, Vietnam, Wallis & Futuna, Western Sahara, Yemen, Zambia, Åland Islands
白俄罗斯。 中国。 古巴, 埃及, 伊朗, 北朝鲜。 俄罗斯, 苏丹, 土耳其。 乌克兰
无水氯化钙用途
用途一：用作冷冻剂，也用于食品加工、制药等
用途二：在食品工业中用作钙质强化剂、螯合剂、固化剂和冷冻用致冷剂。
用途三：作饲料钙补充。
用途四：作凝固剂，我国规定可在豆制品中按生产需要适量使用。
用途五：用作冷冻剂(如冷冻机用冷冻盐水、制冰和制冰棒时用冷冻盐水)、防冻剂、汽车防冻液、灭火剂。用于熔冰和熔雪，棉织物的整理和精加工的阻燃剂。用作胶黏剂和木材防腐剂。是制造无水氯化钙的原料。用于墙壁粉刷及抹灰作业中，增加凝结能力。橡胶生产用作凝析剂。混合淀粉糊用作上胶剂。还用于有色金属冶炼。用作医药品。
用途六：氧、硫吸收剂。食物保护剂。上浆剂。净水剂。防冻剂。
二氯甲烷用途
【用途一】
用作溶剂，也用于有机合成
【用途二】
是不燃性低沸点溶剂，作醋酸纤维素成膜、气溶胶和抗菌素、维生素生产中的溶剂，也用作萃取剂、金属清洗剂等
【用途三】
二氯甲烷是杀菌剂腈菌唑和咪菌唑生产的原料，也是一种很好的溶剂。
【用途四】
萃取溶剂。如用于萃取咖啡豆中的咖啡因。并用作酒花、香辛料油树脂等抽提溶剂。色素稀释剂。
【用途五】
该品除用于有机合成外，还广泛用作醋酸纤维素成膜，三醋酸纤维素抽丝，石油脱蜡，气溶胶和抗生素、维生素、甾族化合物生产中的溶剂，以及金属表面漆层清洗脱脂及脱膜剂。此外，还用于谷物熏蒸和低压冷冻机及空调装置的制冷。在聚醚型尿烷泡沫塑料生产中用作辅助发泡剂，以及用作挤压聚砜型泡沫塑料的发泡剂。
PENG Bo
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我查阅文献发现，替诺福韦 & 拉米夫定，对于新冠可能有作用（请不要自己吃药！请先咨询医生！）。它们都已实现国产化，价格只需几十元。
替诺福韦（TDF）和拉米夫定（3TC）都是经典药，可抑制多种病毒复制，包括乙肝和艾滋。请大家转载本文，让我们听到更多医生朋友的看法。我坚信人类必将能逐步战胜病毒。
本文仅为资料展示！请不要自己吃药！请先咨询医生！
一、替诺福韦：//www.aidsmap.com/news/oct-2022/old-style-tenofovir-really-may-protect-against-covid-large-us-study-finds（症状率下降35%，住院率下降57%，ICU率下降43%）It found that compared with the other two NRTIs, the risk of symptomatic COVID in men taking TDF was reduced by 35%, the risk of hospitalisation by 57%, and the risk of ICU admission by 43% - though the latter result was not statistically significant, as there was only one man who took TDF and was admitted to ICU.
//www.poz.com/article/hepatitis-b-study-revisits-link-tenofovir-covid19（对于高危人群，重症率从36%降为6%，死亡率从10%降为1.5%）Another Spanish team reported results at the 2021 International Liver Congress showing that people taking TDF to treat hepatitis B were significantly less likely to have severe COVID (6% versus 36%) and less likely to die (1.5% versus 10%) than those taking entecavir (Baraclude), another hepatitis B antiviral.
二、拉米夫定：//www.ijmmtd.org/article-details/13463（感染率从48%降至2%，很夸张，真实性未知）About 2% of the participants in the Lamivudine group were COVID positive as compared to 48.4% of the participants were COVID positive in the Non-Lamivudine group.
//www.ncbi.nlm.nih.gov/pmc/articles/PMC8335563/（药理研究显示有潜力，并推荐做实验）In summary, we report here in silico data suggesting Lamivudine as a putative anti-COVID-19 medication.
//www.frontiersin.org/articles/10.3389/fonc.2021.664794/full Another cohort study in Spain showed a lower incidence and severity of COVID-19 in HIV patients receiving Lamivudine and/or other ANNAs´ therapy vs. other HIV patients (76, 77).
三、替诺福韦（TDF）与丙酚替诺福韦（TAF）对比：//pubmed.ncbi.nlm.nih.gov/35848570/ Compared with TAF/FTC, the estimated 18-month risk ratio (95% confidence interval) of documented SARS-CoV-2 infection was 0.65 (0.43, 0.89) for TDF/FTC, 1.00 (0.85, 1.18) for ABC/3TC, and 0.87 (0.70, 1.04) for others. The corresponding risk ratios for COVID-19 hospitalization were 0.43 (0.07, 0.87), 1.09 (0.79, 1.48), and 1.21 (0.88, 1.62).
//pubmed.ncbi.nlm.nih.gov/32589451/ The risk for COVID-19 hospitalization was 20.3 (95% CI, 15.2 to 26.7) among patients receiving TAF/FTC, 10.5 (CI, 5.6 to 17.9) among those receiving TDF/FTC, 23.4 (CI, 17.2 to 31.1) among those receiving ABC/3TC, and 20.0 (CI, 14.2 to 27.3) for those receiving other regimens.
替诺福韦有进口版“韦瑞德”，现在也有国产版。拉米夫定也有国产版。国产版的价格便宜，几十元（如果大量生产，估计可以更便宜）。
本文仅为资料展示！请不要自己吃药！请先咨询医生！
本文仅为资料展示！请不要自己吃药！请先咨询医生！
本文仅为资料展示！请不要自己吃药！请先咨询医生！
编辑于 2022-12-05 15:05・IP 属地广东
新型冠状病毒
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